:sharpen(level=0):output(format=jpeg)/up/3/default/2024-10/Perio-3.jpg "Infection Or Inflammation: The Link Between Periodontal Disease And Systemic Disease")
Reading time: 4 minutes Authors: Gregory J. Seymour- BDS, MDSc, PhD, FRCPath, FFOP(RCPA), FRACDS(Perio), Pauline J. Ford- BDentSt, BDSc, Erica Gemmell- BSc, PhD, Kazuhisa Yamazaki- DDS,PhD.
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Create an accountThere is increasing evidence that chronic infections are associated with cardiovascular diseases (CVDs). Although a large number of potential mechanisms have been postulated, the mechanism by which these infections associate with CVDs is still unclear. A number of hypotheses nevertheless exist, including common susceptibility, systemic inflammation with increased circulating cytokines and inflammatory mediators, direct infection of the blood vessels, and, finally, cross-reactivity or molecular mimicry between bacterial and self-antigens. This final hypothesis is gaining support and will be discussed in this review.
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